John O'Brien Selected Research

Phenmetrazine (Preludin)

3/2017

Test purchase, synthesis and characterization of 3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and para-substituted isomers.

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John O'Brien Research Topics

Disease

26	Dementia (Dementias) 10/2021 - 01/2002
19	Alzheimer Disease (Alzheimer's Disease) 10/2021 - 09/2002
9	Cognitive Dysfunction 01/2022 - 01/2005
5	Lewy Body Disease (Lewy Body Dementia) 07/2022 - 01/2005
5	Stroke (Strokes) 03/2016 - 01/2003
4	Neoplasms (Cancer) 11/2020 - 02/2002
2	COVID-19 10/2021 - 10/2020
2	Premature Birth (Birth, Premature) 04/2018 - 01/2018
2	Substance-Related Disorders (Drug Abuse) 03/2017 - 07/2014
2	Ganglion Cysts (Ganglion) 01/2017 - 06/2004
2	Malaria 01/2014 - 03/2013
2	Squamous Cell Carcinoma of Head and Neck 12/2011 - 03/2002
1	Sleep Initiation and Maintenance Disorders (Insomnia) 03/2022
1	Seizures (Absence Seizure) 03/2022
1	Olfaction Disorders (Cacosmia) 01/2022
1	Kidney Diseases (Kidney Disease) 01/2021
1	Renal Insufficiency (Renal Failure) 01/2021
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 10/2020
1	Tauopathies 10/2020
1	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 10/2020
1	Corticobasal Degeneration 10/2020
1	Hallucinations (Hallucination) 01/2020
1	Dizziness (Lightheadedness) 01/2020
1	Necrosis 01/2019
1	Asthma (Bronchial Asthma) 01/2018
1	Neuroinflammatory Diseases 01/2018
1	Glaucoma 01/2018
1	Retinal Diseases 01/2018
1	Narcolepsy 03/2017
1	Obesity 03/2017
1	Death (Near-Death Experience) 01/2016
1	Altitude Sickness (Mountain Sickness) 01/2016
1	Hypertension (High Blood Pressure) 09/2014
1	Leukoaraiosis 06/2014
1	Tetanus 10/2013
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 07/2013
1	Neuroblastoma 07/2013
1	Pheochromocytoma 07/2013

Drug/Important Bio-Agent (IBA)

9	Pharmaceutical PreparationsIBA 03/2022 - 01/2003
5	Donepezil (Aricept)FDA LinkGeneric 12/2015 - 11/2006
5	LigandsIBA 07/2013 - 02/2002
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2011
4	Memantine (Namenda)FDA Link 12/2015 - 11/2006
3	Mirtazapine (Rexer)FDA LinkGeneric 10/2021 - 07/2011
3	Amyloid (Amyloid Fibrils)IBA 10/2020 - 01/2005
3	Cholinergic Agents (Cholinergics)IBA 01/2020 - 09/2002
3	Proteins (Proteins, Gene)FDA Link 07/2013 - 03/2005
2	3-Iodobenzylguanidine (Iobenguane)IBA 07/2022 - 01/2021
2	VaccinesIBA 10/2021 - 10/2020
2	Apolipoproteins E (ApoE)IBA 01/2020 - 11/2002
2	CytokinesIBA 01/2019 - 04/2018
2	DiamondIBA 10/2018 - 12/2017
2	Antihypertensive Agents (Antihypertensives)IBA 03/2016 - 09/2014
2	LDL CholesterolIBA 09/2014 - 09/2014
2	oxidized low density lipoproteinIBA 09/2014 - 09/2014
2	DNA (Deoxyribonucleic Acid)IBA 03/2013 - 02/2002
2	Antidepressive Agents (Antidepressants)IBA 02/2013 - 07/2011
2	Sertraline (Zoloft)FDA LinkGeneric 02/2013 - 07/2011
2	Cholinesterase Inhibitors (Anticholinesterases)IBA 03/2012 - 11/2006
2	ConnexinsIBA 11/2008 - 06/2004
2	Antipsychotic Agents (Antipsychotics)IBA 07/2008 - 02/2002
2	Rivastigmine (Exelon)FDA LinkGeneric 11/2006 - 04/2005
2	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 03/2003 - 09/2002
1	BenzodiazepinesIBA 03/2022
1	TabletsIBA 03/2022
1	Complement Factor H (Factor H)IBA 01/2021
1	ChromatinIBA 11/2020
1	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 10/2020
1	Minocycline (Cyclops)FDA LinkGeneric 01/2020
1	Interleukin-6 (Interleukin 6)IBA 01/2019
1	Interleukin-13IBA 01/2019
1	InterleukinsIBA 01/2019
1	Interferon-gamma (Interferon, gamma)IBA 01/2019
1	Interleukin-8 (Interleukin 8)IBA 01/2019
1	Interleukin-2 (IL2)IBA 01/2019
1	Interleukin-4 (Interleukin 4)IBA 01/2019
1	Progesterone FDA LinkGeneric 01/2018
1	Vitamin D FDA LinkGeneric 01/2018
1	Amyloid beta-PeptidesIBA 01/2018
1	Modafinil (Provigil)FDA Link 03/2017
1	acetamideIBA 03/2017
1	3-fluorophenmetrazineIBA 03/2017
1	Phenmetrazine (Preludin)FDA Link 03/2017
1	Retinaldehyde (Retinal)IBA 01/2017
1	Oxygen (Dioxygen)IBA 01/2016
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2016
1	pleiotrophin (HARP)IBA 02/2015
1	para-methyl-4-methylaminorexIBA 07/2014
1	Antimalarials (Antimalarial Agents)IBA 01/2014
1	Peptide Hydrolases (Proteases)FDA Link 10/2013
1	Ciliary Neurotrophic Factor (CNTF)IBA 07/2013
1	Type A Botulinum Toxins (Botox)FDA Link 07/2013
1	incobotulinumtoxinA FDA Link 07/2013

Therapy/Procedure

8	Therapeutics 10/2020 - 09/2002
5	Self-Help Devices (Assistive Technology) 01/2021 - 10/2013
2	Drug Therapy (Chemotherapy) 07/2012 - 09/2009
1	Transplantation 01/2016
1	Home Nursing (Nursing, Home) 12/2015
1	Secondary Prevention 09/2014
1	Activities of Daily Living (ADL) 06/2014